Assessment of diagnostic accuracy of dermoscopic structures and patterns used in melanoma detection: A systematic review and meta-analysis
JAMA Aug 09, 2021
Williams NM, Rojas KD, Reynolds JM, et al. - According to this systematic review and meta-analysis, the diagnostic value of dermoscopic structures associated with melanoma detection (eg, shiny white structures, blue-white veil) was confirmed, which adds to the overall pattern's importance and may suggest a hierarchy in the significance of these structures and patterns.
In total, 40 studies involving 22,796 skin lesions and 5,736 melanomas were assessed.
Shiny white structures, pseudopods, irregular pigmentation, blue-white veil, and peppering were the structures and patterns with the highest odds ratios.
Pseudopods, shiny white structures, peppering, and streaks had the highest specificity, on the other hand, irregular pigmentation, blue-white veil, atypical network, and a multicomponent pattern had the highest sensitivity.
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