Kass MA, Heuer DK, Higginbotham EJ, et al. - Researchers sought to determine the cumulative incidence and severity of primary open-angle glaucoma (POAG) after 20 years of follow-up among candidates in the Ocular Hypertension Treatment Study. In total, 1,636 people (mean [SD] age, 55.4 [9.6] years; 931 women [56.9%]; 1,138 White participants [69.6%]; 407 Black/African American participants [24.9%]) were randomized in phase 1 of the clinical trial. Of those, 483 candidates (29.5%) developed POAG in 1 or both eyes (unadjusted incidence). Data reported that the 20-year cumulative incidence of POAG was 55.2% among Black/African American participants and 42.7% among participants of other races. It was noted that the 20-year cumulative incidence for visual field loss was 25.2%. Over the course of the study, only one-fourth of the participants in the Ocular Hypertension Treatment Study developed visual field loss in either eye. This information, combined with a prediction model, may assist clinicians and patients in making informed personalized decisions about ocular hypertension management.