Peters M, et al. - Researchers compared the number and size of interruptions in patients with rheumatoid arthritis (RA) with healthy subjects using high-resolution peripheral quantitative CT (HR-pQCT), and studied the relationship between structural damage and inflammatory markers on conventional radiography (CR) and MRI with interruptions on HR-pQCT, as well as examined the added value of HR-pQCT over CR and MRI. Through CR, MRI, and HR-pQCT, the finger joints of 39 patients with RA and 38 healthy subjects were investigated. Using the Sharp/Van der Heijde method, CRs were scored. In the result, they found more and larger cortical interruptions in the finger joints of patients with RA vs healthy subjects, also after adjustment for findings on CR or MRI, suggesting that HR-pQCT imaging could be of value in addition to CR and MRI for the evaluation of structural damage in patients with RA.