Templeton TW, Goenaga-Díaz EJ, Downard MG, et al. - Researchers performed this prospective, observational study to evaluate the significance of usually used predictors of fitness for extubation to identify the most salient ones that could predict successful extubation following emergence from general anesthesia with a volatile anesthetic in young children. Participants were 600 children from 0 to 7 yr of age. At the time of extubation, they recorded the presence or absence of 9 usually used extubation criteria in children. In 92.7% (556 of 600) of cases, the occurrence of successful extubation was reported. Findings revealed an individual association of each conjugate gaze, facial grimace, eye opening, purposeful movement, and tidal volume greater than 5 ml/kg, with extubation success in pediatric surgical patients following volatile anesthetic. A more rational and robust approach to successful awake extubation may emerge from the use of a multifactorial approach using these predictors.