Assessment of circumferential angle closure with swept-source optical coherence tomography: A community-based study
American Journal of Ophthalmology Feb 24, 2019
Porporato N, et al. - A sum of 1857 individuals were analyzed to comparatively study the diagnostic performance of swept-source optical coherence tomography (SS-OCT, CASIA SS-1000; Tomey Corporation, Nagoya, Japan) vs gonioscopy for angle closure detection. They noted the prevalence of angle closure on SS-OCT, 26.1% for the ≥35% definition, with a sensitivity of 82.5% and specificity of 78.5%. They observed valid first-order agreement coefficient statistics for the 2-quadrant gonioscopic definition of angle-closure with corresponding ≥35%, ≥50%, and ≥75% angle closure definitions for SS-OCT at 0.89, 0.88, and 0.88, respectively. Overall, they suggested SS-OCT with a moderate performance for angle closure detection in comparison to gonioscopy as the reference standard.
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