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Assessment of choriocapillary blood flow changes in response to half-dose photodynamic therapy in chronic central serous chorioretinopathy using optical coherence tomography angiography

BMC Ophthalmology Oct 13, 2020

Liu J, Chen C, Li L, et al. - Researchers conducted the study for quantifying the blood flow changes in the choriocapillaris (CC) of chronic central serous chorioretinopathy (CCSC) patients receiving half-dose photodynamic therapy (PDT) utilizing optical coherence tomography angiography (OCTA). In total, 28 affected eyes and 24 unaffected eyes of 26 CCSC patients receiving half-dose PDT, and 40 eyes of 20 healthy gender- and age-matched subjects were retrospectively recruited in this analysis. Flow signal voids at 6-m follow-up was significantly lower for affected eyes than that at 1-m follow-up. In completely resolved eyes of CCSC patients treated with half-dose PDT, irregular CC flow attenuation persists.

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