Rice D, Ratliff PD, Judd WR, et al. - This retrospective, single center, cohort analysis was undertaken to ascertain whether among chronic kidney disease (CKD) patients who present to the emergency department with sepsis-induced hypotension or septic shock, hospital length of stay (LOS) is impacted by following fluid resuscitation recommendations in the Surviving Sepsis Campaign guidelines. This study involved 106 patients. Stratification of patients into two groups was done depending on the total volume of weight-based crystalloid fluid bolus started within the first three hours of hypotension initiation (< 27 mL/kg and ≥  27 mL/kg). Findings revealed a longer hospital LOS in CKD patients who received guideline-directed fluid resuscitation (≥ 27 mL/kg) for sepsis-induced hypotension or septic shock vs those who received a decreased initial fluid volume.