Terslev L, et al. - Researchers used data from two earlier published Norwegian rheumatoid arthritis (RA) patient cohorts starting therapy, to determine which of the right hand, the dominant hand, or the hand with more clinically swollen joints (SwJ) per se should be preferred, based on inflammatory activity and change during treatment, for unilateral scoring of synovitis by ultrasound in RA cases. By ultrasound, bilateral metacarpophalangeal joint 1–5, proximal phalangeal joint 2+3, and wrists were assessed. For each hand (0–30), they calculated a grey-scale (GS), power Doppler and global synovitis score (GLOESS) by using a 0–3 scoring system. This study included 437 RA patients. Findings revealed that the hand with statistically more inflammatory activity, according to GS, Doppler, and GLOESS sum scores, and that showed a change during therapy, was the hand with clinically more SwJ and is suggested to be potentially the best option for unilateral scoring systems.