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Assessing prevalence and predictors of depression in type 2 diabetes mellitus (DM) patients –The DEPDIAB Study

Diabetes Research and Clinical Practice Jul 30, 2021

Majumdar S, Sinha B, Dastidar BG, et al. - A cross-sectional study was conducted to evaluate the predictors of depression as well as its prevalence in Type 2 Diabetes Mellitus (T2DM) patients. Researchers conducting a cohort of 1,371 T2DM patients from Eastern India suffering from diabetes greater than 1 year assessed in a cross-sectional survey in 9 different hospitals and medical polyclinics in Kolkata, India for depression by administering the 9-item PHQ – 9 and Beck depression scales. They evaluated socioeconomic status by the “Revised Kuppuswamy and BG Prasad socioeconomic scales for 2016”, a validated scoring system for assessing the socioeconomic status of Indian patients. A high prevalence of depression was found in T2DM patients in Eastern India. The results demonstrate that the younger age, female gender, lower socioeconomic status, poor compliance, hypoglycemia, and difficulty in managing day-to-day activities emerged as significant predictors of depression in this study. In patients with depression, recurrent episodes of hypoglycemia were an independent risk factor for suicidal ideation. It was shown that depression was not significantly correlated with comorbidities associated with T2D and surprisingly insulin usage was not associated with increased depression.

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