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Assessing endometrial cancer risk among US women: Long-term trends using hysterectomy-adjusted analysis

American Journal of Obstetrics and Gynecology May 25, 2019

Doll KM, et al. - Researchers examined the changes in the long-term trends in Black-White differences in endometrial cancer (EC) incidence and histology type for women at risk from 1997 to 2014. Using longitudinal Surveillance, Epidemiology, and End Results data and state-level hysterectomy prevalence from the Behavioral Risk Factor Surveillance System, they identified EC incidence of 87/100,000 from 1997-2014 among women over 50 who have not had a hysterectomy. White women displayed a change in EC incidence from 102 (1997-2001) to 86 (2012-2014) cases per 100,000, with a non-significant decreasing linear trend. As per updated hysterectomy-adjusted incidence, EC is identified as the 2nd most common cancer among women over 50 with a uterus, and Black women vs White women are more likely to have EC in the US since 2002. This supports that during the perimenopausal and menopausal years – especially among Black women, a clinical approach of proactive communication and routine screening for early symptoms should be undertaken.
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