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Assessing endometrial cancer risk among US women: Long-term trends using hysterectomy-adjusted analysis

American Journal of Obstetrics and Gynecology Aug 05, 2019

Doll KM, et al. - Researchers sought to determine the changes in the long-term trends in Black-White differences in endometrial cancer incidence and histology type over time for women at risk. They assessed hysterectomy-adjusted incidence rates of endometrial cancer and the proportion of high vs low-risk endometrial cancer, by race, over time, using longitudinal Surveillance, Epidemiology, and End Results data from 1997 to 2014 and state-level hysterectomy prevalence from the Behavioral Risk Factor Surveillance System. Updated hysterectomy-adjusted incidence demonstrates that among women older than 50 years with a uterus, the second most common cancer is endometrial cancer and that black women vs white women have reported endometrial cancer more commonly in the United States since 2002. This emphasizes the necessity for a clinical approach of proactive communication and routine screening for early symptoms in the perimenopausal and menopausal years, especially among Black women. In addition, these findings can notify the equitable distribution of research funding for endometrial cancer and assist in increasing public awareness of this common cancer.
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