Vercellino L, et al. - A pilot study of ¹⁸F-FLT PET was conducted to assess the diagnostic value of this technique in myelofibrosis, ¹⁸F-FLT PET imaging results were compared with bone marrow histology and bone marrow scintigraphy (BMS), the gold standard techniques in this clinical situation. In this study, ¹⁸F-FLT PET seems to be a reliable and convenient technique to evaluate hematopoietic activity in bone marrow. It yields results close to those seen with BMS. In this study population, ¹⁸F-FLT uptake in the axial skeleton and proximal limbs evaluated by SUVmax correlated with the grade of fibrosis. Thus, ¹⁸F-FLT PET may be a helpful tool to measure the severity of myelofibrosis, and to monitor noninvasively the patients' status amid follow-up. Finally, ¹⁸F-FLT PET may be foreseen as an option to BMS.