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Aspirin-exacerbated respiratory disease: Longitudinal assessment of a large cohort and implications of diagnostic delay

International Forum of Allergy & Rhinology Mar 06, 2020

Kshirsagar RS, et al. - Given that aspirin-exacerbated respiratory disease (AERD) refers to the combination of asthma, chronic rhinosinusitis with nasal polyposis (CRSwNP), and acute respiratory tract reactions to ingestion of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), researchers performed a retrospective observational study to ascertain if delay of diagnosis of AERD was correlated with poorer clinical outcomes as well as to describe the role of specialty evaluation in diagnosis. This is the first study identifying diagnostic delay in AERD patients. The sample consisted of 254 patients with incident AERD diagnoses between 2009 and 2016 among Kaiser Permanente Northern California members. A substantial proportion of patients with AERD face a diagnostic delay. Allergy patients are at lower risk for this delay. No association was found between provider specialty at time of diagnosis and delay in diagnosis.
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