Hampton CB, Berliner ZP, Nguyen JT, et al. - This study was attempted to distinguish early radiographic measures that may associate with aseptic tibial component loosening, emphasizing the systematic evaluation of the cement mantle. Using in an institutional implant retrieval database, all total knee arthroplasty (TKA) revisions from 2007-2015 with the primary indication of tibial aseptic loosening were distinguished. Sixty-one TKAs comprised the study group after exclusion criteria. A matched control group of 59 TKAs that had not failed at a minimum of 3 years was distinguished for identification. The outcomes of this study imply that radiographic indicators of poor cement mantle quality associate with later aseptic loosening. This highlights the requirement for surgeons to conduct careful cement technique in order to decrease the risk of TKA failure.