Riba-Llena I, et al. - Whether a load of cerebral small vessel disease (cSVD) and its individual markers, including lacunes, white matter hyperintensities, microbleeds, and enlarged perivascular spaces (EPVS), were correlated with arterial stiffness, was investigated. For this analysis, cSVD markers were assessed in a cohort of 782 hypertensive people without a history of stroke or dementia. Researchers calculated the load of the disease by using an ordinal scale ranging from 0 to 4 (1 point was given for each of the 4 markers examined). By measuring the carotid–femoral pulse wave velocity with an oscillometric automatic device, the arterial stiffness was tested. The arterial stiffness was associated with the total load of the cSVD, particularly with lacunes and basal ganglia EPVS in a cohort of hypertensive people.