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Arterial stiffness is an independent predictor for risk of mortality in patients with type 2 diabetes mellitus: The REBOUND study

Cardiovascular Diabetology Sep 26, 2020

Kim JM, Kim SS, Kim IJ, et al. - This study was undertaken to investigate the advantage of brachial-ankle pulse wave velocity (baPWV) as a noninvasive marker of arterial stiffness for the prediction of all-cause and cause-specific mortality in patients with type 2 diabetes. Researchers conducted a multicenter prospective observational study examining a total of 2,308 patients with type 2 diabetes between 2008 and 2018. Individuals were categorized according to the quartiles of baPWV. The death certificates and patient clinical records were applied to ascertain the cause of mortality. Estimated proportional mortality rates from all causes, cardiovascular, cancer, and other causes were calculated among adults with diabetic status according to their baPWV. They applied Cox regression models to calculate hazard ratios. This long-term, large-scale, multicenter prospective observational cohort study serves evidence that elevated arterial stiffness, as assessed by baPWV, prognosticates the risk of all-cause and cause-specific mortality in type 2 diabetes, supporting the prognostic usefulness of baPWV.

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