Agarwal R - The trajectory of aortic pulse wave velocity (PWV) and blood pressure (BP) in chronic kidney disease (CKD) was determined, and the longitudinal interrelationship of BP (clinic and 24 h ambulatory recording) with the PWV was compared in this study. Over time changes in PWV and its inverse association with the baseline PWV were observed among people with CKD. For the evaluation of PWV and its change over time, the usefulness of an average of clinic BP measurements taken over three visits, but not of single measurements, was demonstrated. With respect to the ability to predict the PWV, differences existed between ambulatory BP monitoring recording during the sleep and awake states. Overall, it was concluded that targeting clinic BP taken on multiple occasions using a standardized methodology or daytime ambulatory systolic BP may slow the progression of arterial damage in non-dialysis CKD.