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Arterial spin-labeling MRI identifies hypervascular meningiomas

American Journal of Roentgenology Aug 03, 2019

Mayercik V, et al. - Via a retrospective study conducted on 39 meningiomas in 34 patients who underwent arterial spin-labeling (ASL) MRI and digital subtraction angiography (DSA) between January 2008 and January 2017, researchers examined whether increased blood flow within meningiomas seen on ASL MRI associated with enhanced tumor vascularity seen on DSA. The mean normalized tumor blood flow (TBF) for meningiomas with tumor blush on DSA was significantly greater in comparison with those without tumor blush, in 27 female and seven male patients. For the group with tumor blush and the group without tumor blush group, the mean normalized TBF was 4.7 ± 1.1 and 1.5 ± 1.1, respectively, for rater 1 and for rater 2, it was 4.9 ± 5.3 and 1.5 ± 1.1, respectively. The intraclass correlation coefficient was outstanding. The area under the ROC curve for using normalized TBF to recognize tumor vascularity on DSA was 0.82, and a normalized TBF cut point of 2.7 generated 88% sensitivity and 67% specificity. Hence, for identifying hypervascular meningiomas, ASL MRI demonstrated potential as a noninvasive screening tool.
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