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Appropriate timing of surveillance intervals with whole-body 18F-FDG PET/CT following treatment for sinonasal malignancies

European Journal of Radiology Jul 12, 2019

Ozturk K, et al. - Eighty patients who underwent a total of 197 posttreatment whole-body 18F-FDG PET/CT examinations for sinonasal malignancy were retrospectively analyzed by the experts in order to determine the ideal timing of posttreatment whole-body 18F-FDG PET/CT examination as routine surveillance to assess local recurrence, lymph node metastasis, and distant metastasis of sinonasal malignancies and to examine the impact of 18FF-FDG PET/CT on survival. The negative predictive value and positive predictive value of the 18F-FDG PET/CT assessments for the prediction of the overall recurrence in 1-3 months and >18 months were greater than for recurrence detection in <1 month, 3-6 months, 6-12 months, and 12-18 months, recognizing the time intervals of posttreatment 18F-FDG PET/CT scans. Positive findings on 18F-FDG PET/CT scans were also concluded as independent predictors of worse overall survival. Hence, whole-body 18F-FDG PET/CT was discovered as proficient in recognizing recurrences post-treatment, using an optimal time interval for scanning of 1-3 months and >18 months following therapy.

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