• Profile
Close

Appropriate number of adjuvant chemotherapy cycles for patients with stage 2 or 3 gastric cancer after curative gastrectomy: A multicenter cohort study

Annals of Surgical Oncology Jan 13, 2021

Jeong SH, Yoo MW, Son YG, et al. - Researchers sought to determine the satisfactory minimum number of adjuvant chemotherapy (AC) cycles needed to attain an oncologic benefit for gastric cancer. They analyzed data from 925 patients who underwent curative radical gastrectomy and then were given AC for pathologic stage 2 or 3 gastric cancer at 27 institutions in South Korea from January 2012 to December 2013. Of these patients, 661 (71.5%) completed 8 cycles of AC and 264 patients (28.5%) did not. Outcomes suggest that 6 or 7 AC cycles results in disease-free survival (DFS) similar to that noted for 8 AC cycles as an adjuvant treatment for gastric cancer. The mean DFS of patients who completed 6 AC cycles (72.4 months) and those who completed 7 AC cycles (63.7 months) did not differ significantly vs the mean DFS of patients who completed 8 AC cycles (69.3 months). However, the mean DFS of the patients who completed 5 AC cycles (48.2 months) and those who completed 1–4 AC cycles (62.9 months) was significantly lower than the DFS of those who completed 8 AC cycles.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay