Nanditha S et al. – This systematic review evaluated the value of platelet–rich fibrin (PRF) in different areas of surgery. The authors concluded that long–term studies are required in distinct fields to establish the effectiveness of PRF. Possibilities of this application are huge, which include newer approaches toward transplant and burn cases.

Methods

• Systematic reviews, randomized control trials, pilot studies, and case reports were included in this review.

Results

• Positive outcomes were recorded in most of the 25 included studies.
• The overall success rate with PRF usage was 78%.
• In 2 studies, no differences were observed between test and control groups and 3 studies showed no significant improvements with PRF.