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Apparent diffusion coefficient values obtained by unenhanced MRI predicts disease-specific survival in bladder cancer

Clinical Radiology Jul 07, 2018

Sevcenco S, et al. - In this cross-sectional study, the researchers assessed if apparent diffusion coefficient (ADC) measurements obtained by MRI could predict disease-specific survival (DSS) in bladder cancer patients and compare it with recognized clinico-pathological prognostic factors. Participants in the study were 51 patients with suspected bladder cancer receiving diagnostic 3 T diffusion-weighted imaging of the bladder prior to transurethral resection of the bladder or radical cystectomy. In these patients, ADC measurements attained by unenhanced MRI could predict DSS. The most accurate clinic-pathological predictors of DSS were muscle invasiveness and vascular invasion. It was noted that an artificial neural network classifier combining clinic-pathological factors and ADC values achieved high predictive accuracy.

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