Zhang D, et al. - In this retrospective study, the researchers intended to ascertain which region of interest (ROI) placement method of apparent diffusion coefficient (ADC) measurement has the best performance for predicting pathological complete response (PCR) at two cycles of neoadjuvant chemotherapy (NAC) according to different tumour shrinkage patterns of luminal breast cancer, as well as to evaluate the evaluative accuracy of ADC value combined with other clinicopathological indicators. Study participants were 61 patients who underwent NAC for histopathologically confirmed breast cancer. Data reported that the methods for measuring ADC values differ across different shrinkage patterns of luminal tumours. The findings demonstrated that oestrogen receptor (ER), ΔADC% and tumour diameter reduction (ΔD%) were independent factors in assessing the PCR.