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APF530 versus ondansetron, each in a guideline-recommended three-drug regimen, for the prevention of chemotherapy-induced nausea and vomiting due to anthracycline plus cyclophosphamide–based highly emetogenic chemotherapy regimens: A post hoc subgroup analysis of the Phase III randomized MAGIC trial

Cancer Management and Research Aug 21, 2017

Schnadig ID, et al. – For the prevention of chemotherapy-induced nausea and vomiting (CINV) due to anthracycline plus, this study planned to examine the efficacy of APF530 versus ondansetron, each in a guideline–recommended three–drug regimen. In patients receiving anthracycline plus cyclophosphamide (AC)–based highly emetogenic chemotherapy (HEC), APF530 plus fosaprepitant and dexamethasone effectively prevented CINV.
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