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APACHE II score validation in emergency abdominal surgery. A post-hoc analysis of the InCare trial

Acta Anaesthesiologica Scandinavica Sep 24, 2019

Hansted AK, et al. - In emergency abdominal surgical patients, researchers evaluated the predictive value of the Acute Physiology And Chronic Health Evaluation (APACHE) II score, as well as compared the APACHE II score with the American Society of Anesthesiologists (ASA) physical status score and the Charlson Comorbidity Index (CCI). The study sample consisted of adult patients (n = 885) undergoing emergency abdominal surgery screened for enrolment in the InCare trial from October 2010 to November 2012. Data reported that all-cause 30-day mortality was 5.0%, 90-day mortality was 8.9%, and a total of 7.9% of the patients were admitted to the intensive care unit. The authors discovered that the AUROC of the APACHE II score was 0.72 for 30-day mortality, 0.70 for 90-day mortality and 0.65 for admission to the intensive care unit. In predicting 90-day mortality, the CCI performed better. All other outcomes for the ASA score and CCI were similar to the APACHE II score. In emergency abdominal surgical patients, the APACHE II score anticipated mortality moderately and admission to an intensive care unit poorly.
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