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APACHE II score validation in emergency abdominal surgery: A post hoc analysis of the InCare trial

Acta Anaesthesiologica Scandinavica Jan 30, 2020

Hansted AK, et al. - As a high risk of morbidity and mortality is seen among patients undergoing emergency abdominal surgery and it is crucial to precisely recognize high-risk patients, and since there is a necessity to validate the Acute Physiology and Chronic Health Evaluation (APACHE) II score in a larger heterogeneous population prior to implementation, so, researchers evaluated the predictive value of the APACHE II score in emergency abdominal surgical patients (n = 885). They also performed a comparison between the APACHE II score vs the American Society of Anesthesiologists physical status score vs the Charlson Comorbidity Index (CCI). Thirty-day mortality was the primary outcome. The APACHE II score yielded an AUROC (95% confidence interval) of 0.72 (0.65-0.80), 0.70 (0.64-0.76), and 0.65 (0.59-0.71) for 30-day mortality, 90-day mortality, and for admission to the intensive care unit, respectively. Better performance of CCI was evident in the prediction of 90-day mortality. Findings revealed that a moderate prediction of mortality and a poor prediction of admission to intensive care unit was afforded by the APACHE II score among emergency abdominal surgical patients.
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