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Aortic valve replacement improves survival in severe aortic stenosis with gradient–area mismatch

European Journal of Cardio-Thoracic Surgery Oct 18, 2017

Mo Y, et al. - This study sought to investigate whether and in which patients with catheter-derived low pressure gradient (PG, <40 mmHg) severe (aortic valve area ≤ 1 cm2) aortic stenosis and preserved left ventricular ejection fraction, early aortic valve replacement (AVR) could improve survival. In severe aortic stenosis (SAS), AVR seemed improving survival regardless of the gradient and flow. This seemed to favor an ‘early-AVR’ rather than a ‘watchful waiting’ strategy.
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