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Aortic root dilatation and aortic-related complications in children after tetralogy of Fallot repair

Circulation: Cardiovascular Imaging Dec 21, 2018

Grotenhuis HB, et al. - Researchers compared 768 pediatric tetralogy of Fallot (TOF) with 304 controls regarding the severity, progression rate, and risk factors for aortic root dilatation (ARD). Further, they studied its relationship to complications including aortic regurgitation. Five hundred ninety-two (77%) had usual TOF, 41 (5.3%) TOF-type double outlet right ventricle, and 135 (17.6%) TOF with pulmonary atresia. Data reveal that ARD is common before and after TOF repair, but in the majority of pediatric TOF patients, aortic root dimensions remain stable. During childhood, progressive ARD and aortic-related complications are distinctly uncommon.
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