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Anxiety, depression and quality of life in patients with a treated or untreated unruptured intracranial aneurysm

Journal of Clinical Neuroscience Aug 24, 2017

Li YP, et al. – The present study was undertaken to evaluate the influence of unruptured intracranial aneurysm (UIA) treatment (surgery clipping and endovascular coiling) on behavior such as anxiety and depression, as well as the quality of life (QoL). The results obtained from the study indicate that the QoL of patients with endovascular coiling seemed to be superior to those of surgical clipping, with no difference in anxiety or depression.

Methods

  • A series of two hundred ninety-six UIA patients (including 162 treated and 134 untreated) were examined.
  • After that, postal questionnaires were sent to these patients, included Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale(SDS) and Short Form-36(SF-36).

Results

  • Altogether, one hundred ninety-eight (66.9%) patients responded to the questionnaires.
  • Researchers reported that patients with surgical clipping or endovascular coiling had a significant improvement in the physical function, body pain and mental health domains.
  • They did not observe a significant difference in the SAS, SDS and SF-36 between the clipping and coiling group, while SF-36 in body pain domain was significantly higher in the coiling group.
  • It was noted that patients diagnosed five years ago with or without treatment got a lower score of SAS and SDS, higher SF-36 score than those diagnosed one year ago.
  • The findings suggested that neurological complications might be an important factor causing a lower quality of life.

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