Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2
Gynecologic Oncology | Sep 14, 2017
Oza AM, et al. - Experts wanted to characterize the antitumor activity and safety profile of the oral poly(ADP-ribose) polymerase inhibitor rucaparib in patients with relapsed high-grade ovarian carcinoma (HGOC). Results of this study outlined the antitumor activity of rucaparib in advanced BRCA1/2-mutated HGOC and a manageable safety profile.
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