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Antiphospholipid score is a novel risk factor for idiopathic osteonecrosis of the femoral head in patients with systemic lupus erythematosus

Rheumatology Dec 11, 2018

Kato M, et al. - Experts identified the effect of antiphospholipid (aPL) on the development of idiopathic osteonecrosis of the femoral head (ION) using aPL score (aPL-S). They conducted a single-centre retrospective study comprising 88 consecutive SLE patients who underwent MRI of the hip joints from January 2000 to March 2017. In SLE, high aPL-S was identified as an important risk factor for ION development, thereby,suggesting the involvement of aPL-induced coagulopathy in the pathophysiology of lupus ION. total hip arthroplasty was received more frequently by the patients with high aPL-S than those without aPL; as seen on Kaplan–Meier analysis.
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