Lange KN, et al. - In view of identifying fewer incisional infectious complications than expected after CS-HIPEC with mitomycin C (MMC), researchers investigated the antimicrobial properties of HIPEC perfusate fluid. They observed considerable antimicrobial properties of HIPEC perfusate. These antimicrobial properties varied between patients and were stronger against E. coli than against S. aureus. Further studies of HIPEC carrier solutions and chemotherapy agents could provide help in reduction of surgical-site infection and thus enhanced patient recovery.