Mendivil CO, et al. – This cross–sectional study was performed to examine the association between antibodies against glutamic acid decarboxylase (GADA), a major antigen from beta cells, and indices of whole–body insulin resistance (IR) and beta–cell capacity/insulin secretion in nondiabetic adults. Investigations revealed that GADA positivity was frequent and likely related to impaired beta–cell function among nondiabetic adults.