Antibiotic treatment in the first week of life impacts the growth trajectory in the first year of life in term infants
Journal of Pediatric Gastroenterology and Nutrition Jun 27, 2019
Kamphorst K, et al. - In this prospective observational birth cohort study, researchers explored the connection between growth and antibiotics, given in the first week of life and antibiotic courses later in the first year of life. The study sample consisted of 436 term infants with 151 receiving broad-spectrum antibiotics for suspected neonatal infection (AB+), and 285 healthy controls (AB−) was followed during their first year. In the first week of life, decreased growth was noted after antibiotics, while increased growth was noted in the first year of life after subsequent antibiotic course(s) in term-born infants. The association with growth may, therefore, be determined by the timing of antibiotics.
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