Heal C, Gorges H, van Driel ML, et al. - In this cross-sectional analysis of data from the Registrar Clinical Encounters in Training (ReCEnT) study, researchers ascertained the prevalence and relationships of systemic antibiotic prescription for impetigo by early-career general practitioners (GPs) (GP registrars in their first 18 months in general practice). According to results, cephalexin was the most common systemic antibiotic prescribed. Variables independently linked to the prescription of systemic antibiotics were an inner regional (compared with the major city) location, seeking in-consultation information or advice and ordering pathology. For a high proportion of initial impetigo presentations, Australian early-career GPs prescribe systemic antibiotics (the majority broad-spectrum). The guidelines for impétigo should clearly specify criteria for systemic prescription of antibiotics and individual choice of antibiotics. It is important to further explore the role of non-antibiotic treatment and topical antiseptics.