AlSaeed T, et al. - Authors ascertained the minimum bactericidal concentrations (MBCs) and minimum inhibitory concentrations (MICs) of metronidazole, ciprofloxacin, minocycline, Augmentin (GlaxoSmithKline, Research Triangle Park, NC), and tigecycline against common endodontic pathogens. They also assessed ex vivo the antibacterial efficacy and discolouration effect of triple antibiotic paste (TAP), Augmentin, and tigecycline at different concentrations using a slow-release hydrogel scaffold. Findings suggested a reduction in the bacterial growth significantly with minimal colour change by TAP, Augmentin, and tigecycline in a hydrogel at 1 mg/mL. When comparing the log10 colony-forming units of all experimental groups, significant differences were found.