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Anti-TNFα treatment in children and adolescents with combined inflammatory bowel disease and autoimmune liver disease

Journal of Pediatric Gastroenterology and Nutrition Jan 18, 2018

Nedelkopoulou N, et al. - As a part of this research, experts attempted to appraise the efficacy of anti-tumor necrosis factor (anti-TNFα) therapy in the management of inflammatory bowel disease (IBD) and autoimmune liver disease (AILD). In patients with AILD, IBD could be aggressive, thereby warranting an escalation to anti-TNFα or switching to other biologics. It was deduced that anti-TNFα did not impair liver function and improved gut disease in maximum patients. This finding illustrated that anti-TNFα therapy could be beneficial and safe.
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