Davey MS, Hurley ET, et al. - A systematic review of randomized control trials was conducted to assess the efficacy of platelet-rich plasma (PRP) to augment anterior cruciate ligament (ACL) reconstruction. Using Preferred Reporting for Systematic Reviews and Meta-Analyses guidelines, two independent reviewers selected the MEDLINE, The Cochrane Library, and EMBASE databases for applicable RCTs analyzing the efficacy of PRP in ACL reconstruction. They conducted a meta-analysis on the papers involving bone-patellar tendon-bone (BPTB) grafting. This research included a sum of 765 individuals. No significant difference was found in the visual analog scale score in the BPTB group, or tibial filling defects. This research obtained that the current level I data does not support the application of PRP to enhance graft healing, improve donor-site morbidity, reduce postoperative pain levels, or improve functional outcomes following ACL reconstruction.