Kamla I, et al. - In this prospective multicenter cohort study, researchers analyzed the incidence of prenatal diagnosis of visible congenital malformations (VCMs), one of the principal causes of disability in the world, in a low-resource setting with no policy on an antenatal diagnosis of VCMs. This investigation was conducted in 10 randomly selected maternity units of Yaoundé, Cameroon from July 2015 to June 2016. One hundred eighty-nine cases of VCMs out of a total of 21,113 births were identified. Data reported that VCMs incidence was 9 per 1,000 births. Malformations of the skeletal, neurological, and gastrointestinal systems were the main VCMs. Hydrocephalus has been the most diagnosed VCM antenatally. According to findings, the prevalence of VCMs in the resource-limited setting is high, with very low rates of antenatal diagnosis. Overall, the study highlights the importance of VCM's antenatal diagnosis, often overlooked in the setting. The goal is to reduce maternal and fetal morbidity in a setting that is already burdened with high maternal and neonatal mortality.