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Angiogenic factor screening in women with mild preeclampsia–New and significant proteins in plasma

Cytokine Nov 02, 2017

Charkiewicz K, et al. - Researchers performed this study on women with mild preeclampsia (PE), to analyze a panel of 60 angiogenic factors (pro-angiogenic and antiangiogenic) in their plasma. It was concluded that protein factors may play a crucial role in the pathogenesis of preeclampsia, and there are many proteins that have not been studied in PE to date. Since no prior studies analyzed the leukaemia inhibitory factor (LIF), follistatin, hepatocyte growth factor (HGF), heparin-binding EGF-like growth factor (HB-EGF) and platelet-derived growth factor BB (PDGF-BB) concentrations in the plasma of women with PE, findings of this study indicate that these proteins are new factors that can play an important role in the pathomechanisms of PE.
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