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Angina severity, mortality, and healthcare utilization among veterans with stable angina

Journal of the American Heart Association Aug 06, 2019

Owlia M, Dodson JA, King JB, et al. - In this retrospective cohort analysis of veterans in the United States with stable angina, researchers examined the links between Canadian Cardiovascular Society (CCS) class and all-cause mortality and healthcare utilization. They extracted CCS classifications from clinical notes by using natural language processing. They excluded veterans with a previous diagnosis of coronary artery disease. A median follow-up of 3.4 years revealed 4.58, 4.60, 6.22, and 6.83 per 100 person-years as all-cause mortality rates for CCS classes I, II, III, and IV, respectively. For all-cause mortality, multivariable adjusted hazard ratios comparing CCS II, III, and IV with those in class I were 1.05, 1.33, and 1.48, respectively. For all-cause hospitalization, for acute coronary syndrome hospitalizations, for heart failure hospitalizations, for atrial fibrillation hospitalizations, for percutaneous coronary intervention, and for coronary artery bypass grafting surgery, the multivariable hazard ratio comparing CCS IV with CCS I were 1.20, 1.25, 1.00, 1.05, 1.92, and 2.51, respectively. Findings revealed a positive association of natural language processing–extracted CCS classification with all-cause mortality and healthcare utilization. This implies that anginal symptom evaluation and documentation is important.
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