Perez E, Viziano A, Al-Zaghal Z, et al. - In this investigation, researchers explored an appropriate surgical strategy for delivering local hypothermia in patients using anatomical and radiologic measurements and experimental measurements from cadaveric human temporal bones. Ten human cadaveric temporal bones have been scanned with micro-computed tomography and characterized by anatomical features and measurements anticipating the visibility of the round window (RW). They used the St. Thomas Hospital (STH) classification to record degree of RW visibility with and without placement of custom hypothermia probe. Data reported that the average facial recess area was 13.87 ± 5.52 mm². The introduction of the cooling probe by either approach did not impede the RW or cochleostomy visualization as determined by STH grading. It was noted that the average temperatures at RW utilizing the FR approach decreased by 4.57 ± 1.68 °C for RW, whereas utilizing the myringotomy approach decreased by 4.11 ± 0.98 °C for RW. Findings suggested that local application of therapeutic hypothermia is clinically feasible through the approaches to facial recess and myringotomy without limiting the optimal visualization of the surgery.