Anatomical characteristics of the left atrium and left atrial appendage in relation to the risk of stroke in patients with vs without atrial fibrillation
Circulation: Arrhythmia and Electrophysiology Jul 25, 2021
Smit JM, Simon J, El Mahdiui M, et al. - Researchers analyzed two large and distinct patient cohorts with and without known atrial fibrillation (AF) to assess the association between left atrial appendage (LAA) morphology and previous stroke and/or transient ischemic attack (TIA). Participants included patients with and without drug-refractory AF who had computed tomography before transcatheter AF ablation, or clinically indicated for suspected coronary artery disease. On the basis of predefined morphology classification criteria, LAA was categorized by 3 readers in consensus as chicken wing, swan, cauliflower or windsock. In this study with 1813 patients (mean age 59 ± 11 years, 42% female), an independent connection of swan morphology of the LAA with prior stroke and/or TIA was found not only in patients with known AF but also in those not previously diagnosed with AF.
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