Liu XJ, et al. - Researchers planned this work with the aim to determine the safety of robotic stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC) patients and its related factors. In this work, ≥ grade 2 hepatic adverse reactions were seemed correlated with total liver volume and normal liver volume after SBRT treatment on HCC patients. Therefore, they recommended ensuring a total liver volume >1,162 mL and a normal liver volume >1,148 mL to improve therapeutic safety when applying the fractionated scheme of 45 Gy/3f in SBRT for HCC patients.