Hawryluk GWJ, Nielson JL, Huie JR, et al. - Via this prospective observational study (2004-2010) including neurocritical care patients from a single level I trauma center, researchers sought to determine the intracranial pressure (ICP) values that are normal for these patients. Further, they investigated the intracranial pressure threshold that is most strongly linked with Glasgow Outcome Scale score at hospital discharge. For 523 patients in the study, 70.7% of whom were men (n = 370), 72.1% had a traumatic brain injury (n = 377). There were 4,090,964 1-minute ICP measurements were recorded (7.78 years of recordings). The most commonly recorded ICP values were 8 to 9 mm Hg; these values may reflect normal values. In studied patients, an ICP threshold of 19 mm Hg was strongly linked with outcome; lower intracranial pressure values were linked with outcome in surviving patients. Intracranial pressure values greater than 19 mm Hg were associated with mortality.