Dohnalek HM, et al. - The nature and frequency of electronic nicotine delivery system (ENDS) injuries over a 10-year study period (2008-2017) were characterized using data from the National Electronic Injury Surveillance System. From 2008 to 2017, 49 incidents were reported, including 18 cases in 2017, 25 cases in 2016, five cases in 2015, and one case in 2013. Findings thereby suggest a significant rise in the number of ENDS-related injuries over the study period mirroring the growth of the ENDS market. Particularly, males under the age of 45 years displayed an increase. In view of the expected increase in the use of ENDS, researchers emphasize physicians be familiarized with the nature of associated injuries.