Bouaou K, et al. - In this retrospective study, researchers computed aortic time-resolved pressure fields of healthy subjects from 4D flow MRI and defined relevant pressure-based markers while studying their association with age, LV remodeling, tonometric augmentation index (AIx) and pulse wave velocity (PWV). Study participants included 47 healthy subjects (age: 49.5 ± 18 years, 24 women). Using linear regression, Wilcoxon rank sum test, Bland–Altman analysis and intraclass correlation coefficients (ICC), investigators found that 4D flow MRI relative aortic pressures were consistent with physiological knowledge as shown by their significant volumetric and temporal variations with age and their independent relationship with LV remodeling and augmentation index.