Zhu M, et al. - The efficacy and viability of the subcostal approach to quadratus lumborum block (QLB) after laparoscopic nephrectomy were examined. Researchers randomly divided 60 patients who underwent laparoscopic nephrectomy into the subcostal approach to QLB group (QLB group, n = 30) and the control group (C group, n = 30). Ultrasound-guided subcostal approach to QLB was undertaken in all patients in an ipsilateral parasagittal oblique plane at the L1–L2 level. They administered 0.4 cc/kg of 0.3% ropivacaine to the QLB group, and 0.4 cc/kg of 0.9% saline to the C group. Postoperatively, all the patients were attached with a patient-controlled intravenous analgesic pump with sufentanil. The QLB group vs C group had significantly lower sufentanil consumption within the first 24 h after surgery, had significantly lower remifentanil consumption intraoperatively, had a lower number of patients requiring rescue analgesia, had significantly earlier time to recovery of intestinal function and mobilization time after surgery and had a significantly lower incidence of postoperative nausea and vomiting. Further, they observed significantly higher Bruggemann comfort scale scores at 6 h and 12 h in the QLB group. These findings thereby support the efficacy of the ultrasound-guided subcostal approach to QLB as an analgesic technique in patients undergoing laparoscopic nephrectomy.