Anaemia and its effects on tumour regression grade and survival following chemotherapy in adenocarcinoma of the oesophagus
Journal of Gastrointestinal Oncology Oct 01, 2018
Boucher ANC, et al. - In this prospective study, researchers examined if anaemia impacts on survival and the effectiveness of chemotherapy, in adenocarcinoma of the oesophagus for those undergoing neoadjuvant chemotherapy and then surgical resection. Participants in the study were 268 patients who received neoadjuvant chemotherapy for oesophageal adenocarcinoma. They did not find a statistical association between those with pre-chemotherapy anaemia and tumor regression grading (TRG) or those with anytime anaemia. Findings suggested an association of anaemia with poorer overall survival time, with lower haemoglobin levels reducing prognosis. No association was found between anaemia and chemotherapy response in oesophageal adenocarcinoma.
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