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An observational study to evaluate the effect of different epidural analgesia regimens on dynamic pain scores in patients receiving epidural analgesia for postoperative pain relief after elective gynecological surgery

Journal of Anaesthesiology Clinical Pharmacology Oct 16, 2018

Singh M, et al. - In patients undergoing elective gynecological surgery, researchers assessed the impact of different epidural analgesia regimens on the postoperative dynamic pain scores. A total of 187 patients were included. Postoperatively, these subjects were given either bupivacaine 0.125% + morphine 0.1 mg/mL (group BM) or bupivacaine 0.125% + fentanyl 2 μg/mL (group BF) or bupivacaine 0.125% + clonidine 1 μg/mL (group C1) or bupivacaine 0.125% + clonidine 2 μg/mL (group C2) by continuous epidural infusion @ 5 mL/hour. As per observations, better postoperative analgesia, better patient satisfaction and significantly lower side effects were offered by combination of clonidine 2 μg/mL to 0.125% bupivacaine @ 5 mL/hour in combined spinal epidural vs combination of bupivacaine with opioids.

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